耿合员;谭文杰;

• 1:中国疾病预防控制中心病毒病预防控制所病毒病应急技术中心

摘要(Abstract)：

冠状病毒是自然界中广泛存在的一大类家族,人和多种动物易感。人冠状病毒感染后,通常引起普通感冒症状,严重者能造成死亡。冠状病毒广泛的宿主性以及自身基因组的结构特征使其在进化过程中极易发生基因重组,呈现遗传多样性;新亚型及新的冠状病毒在此过程中不断出现。本文针对新近出现的冠状病毒,尤其是SARS样冠状病毒(SARS-like-CoVs)以及2012年发现的新型人冠状病毒EMC(HCoV-EMC)的基因组结构特征及冠状病毒跨种属传播机制的最新研究进展作简要论述。

关键词(KeyWords)： SARS样冠状病毒;人冠状病毒EMC;基因组结构;跨种属传播

Abstract:

Keywords:

基金项目(Foundation): 国家973课题(2011CB504704);; 传染病重大专项(2011ZX10004-001)

作者(Authors): 耿合员;谭文杰;

DOI: 10.13242/j.cnki.bingduxuebao.002353

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